If you'd like to create hand-lettered printables, consider taking a custom lettering class so you can edit your designs in Illustrator. Hand lettering is an excellent way to make a printable truly custom.
The great thing about printables for personal use is that you don't need to have a fancy printer or pay a printing company a fortune. Simply print graphics at home with an inkjet or color laser printer. You can find a printer for as little as $60 or upwards of $2000. Don't think you need an expensive printer to create incredible graphics. A printer in the $100 range should work fine.